Motif ID: HOX{A5,B5}.p2

Z-value: 0.832


Transcription factors associated with HOX{A5,B5}.p2:

Gene SymbolEntrez IDGene Name
HOXA5 3202 homeobox A5
HOXB5 3215 homeobox B5

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
HOXA5chr7_-_271497500.243.6e-01Click!
HOXB5chr17_-_440263210.068.2e-01Click!


Activity profile for motif HOX{A5,B5}.p2.

activity profile for motif HOX{A5,B5}.p2


Sorted Z-values histogram for motif HOX{A5,B5}.p2

Sorted Z-values for motif HOX{A5,B5}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of HOX{A5,B5}.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_+_5289079 2.325 NM_001040661
NM_153247
SLC29A4

solute carrier family 29 (nucleoside transporters), member 4

chr12_+_53241365 1.296 NM_001165975
PDE1B
phosphodiesterase 1B, calmodulin-dependent
chr4_-_189263395 1.119 NM_173553
TRIML2
tripartite motif family-like 2
chr1_+_246682699 1.074 NM_001004136
OR2T2
olfactory receptor, family 2, subfamily T, member 2
chr19_-_47040347 0.970 NM_173506
LYPD4
LY6/PLAUR domain containing 4
chr3_-_166397142 0.958 NM_014926
SLITRK3
SLIT and NTRK-like family, member 3
chr17_+_6620275 0.951 NM_153230
FBXO39
F-box protein 39
chr2_+_234266250 0.945 NM_001072
UGT1A6
UDP glucuronosyltransferase 1 family, polypeptide A6
chr1_+_154855709 0.930 NM_021817
HAPLN2
hyaluronan and proteoglycan link protein 2
chr17_-_44249379 0.877 NM_001130918
TTLL6
tubulin tyrosine ligase-like family, member 6
chr12_-_6668680 0.868 ZNF384
zinc finger protein 384
chr3_-_197023096 0.831 MUC4
mucin 4, cell surface associated
chr16_-_56562512 0.814 NM_001135639
NM_001297
CNGB1

cyclic nucleotide gated channel beta 1

chrX_+_48265107 0.806 NM_006579
EBP
emopamil binding protein (sterol isomerase)
chr19_+_51190178 0.802 NM_001080402
CCDC61
coiled-coil domain containing 61
chr20_-_49852353 0.788 NM_020436
SALL4
sal-like 4 (Drosophila)
chrX_+_100220491 0.775 NM_021637
TMEM35
transmembrane protein 35
chr19_-_54958326 0.772 NM_021733
TSKS
testis-specific serine kinase substrate
chr11_+_4859624 0.709 NM_001004759
OR51T1
olfactory receptor, family 51, subfamily T, member 1
chr6_+_31651319 0.706 NM_000594
TNF
tumor necrosis factor

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 9 of 9 entries
enrichment   p-value GO term description
1.77 4.20e-04 GO:0006952 defense response
1.75 1.97e-03 GO:0006955 immune response
1.60 5.12e-04 GO:0002376 immune system process
1.55 3.52e-02 GO:0007154 cell communication
1.39 4.11e-02 GO:0007166 cell surface receptor linked signaling pathway
1.29 2.91e-03 GO:0023052 signaling
1.24 1.18e-05 GO:0050896 response to stimulus
1.24 5.04e-04 GO:0032501 multicellular organismal process
1.14 4.84e-02 GO:0065007 biological regulation

Gene overrepresentation in compartment category:

Showing 1 to 10 of 10 entries
enrichment   p-value GO term description
1.46 9.51e-06 GO:0044459 plasma membrane part
1.42 4.22e-02 GO:0031226 intrinsic to plasma membrane
1.42 4.80e-02 GO:0005887 integral to plasma membrane
1.39 1.08e-03 GO:0005576 extracellular region
1.38 2.63e-09 GO:0005886 plasma membrane
1.37 7.09e-09 GO:0071944 cell periphery
1.20 2.48e-03 GO:0031224 intrinsic to membrane
1.19 6.40e-03 GO:0016021 integral to membrane
1.18 1.65e-03 GO:0044425 membrane part
1.14 1.39e-02 GO:0016020 membrane

Gene overrepresentation in function category:

Showing 1 to 6 of 6 entries
enrichment   p-value GO term description
4.57 3.52e-03 GO:0003823 antigen binding
2.47 2.01e-02 GO:0005539 glycosaminoglycan binding
1.43 3.82e-02 GO:0004888 transmembrane receptor activity
1.41 5.21e-03 GO:0004872 receptor activity
1.34 2.35e-02 GO:0004871 signal transducer activity
1.34 2.35e-02 GO:0060089 molecular transducer activity